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*'''Adrenaline''', 0.3-0.5mg in adults, given intramuscularly, is the most important initial therapy.<ref name=SURF>{{cite web|url=http://www.mastcellssjukdom.se/wp-content/uploads/2015/12/Nationella_rekommendationer_%C3%B6verk%C3%A4nslighetsreaktioner_kontrastmedel__PDF_2014-10-17.pdf|title=Hypersensitivity reactions against contrast media - Swedish Society of Uroradiology [Swedish: Överkänslighetsreaktioner mot kontrastmedel – SURFs kontrastmedelsgrupp] ], 2014-10-17}}</ref>
*'''Peripheral venous catheter''' and IV fluids are needed<ref name=SURF/>
*'''Oxygen saturation''', '''pulse ''' and '''blood pressure ''' are monitored.<ref name=SURF/>
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In case of a '''contrast medium reaction''', a patient should be evaluated for the presence of the following symptoms and be medicated accordingly. Anaphylaxis is a more severe allergic reaction whose diagnostic criteria generally include low blood pressure and/or respiratory distress,<ref name="KimFischer2011">{{cite journal|last1=Kim|first1=Harold|last2=Fischer|first2=David|title=Anaphylaxis|journal=Allergy, Asthma & Clinical Immunology|volume=7|issue=Suppl 1|year=2011|pages=S6|issn=1710-1492|doi=10.1186/1710-1492-7-S1-S6}}</ref> and indicate the attention of an anesthesiologist or corresponding clinician on duty.
