Radlines is in most ways a non-profit and ad-free alternative to Radiopaedia, which is currently the most comprehensive wiki-based reference work in radiology. Radiopaedia is a "business" owned by Investling.com,<ref>{{cite web|url=http://investling.com/|title=Our Businesses|accessdate=2018-05-14|website=Investling.com}}</ref> making profit by advertising and paid subscription. Radlines, on the other hand, is able to run on donations and volunteer time alone.
Furthermore, Radiopedia by default uses the [https://creativecommons.org/licenses/by-nc-sa/3.0/ Creative Commons Attribution-NonCommercial-ShareAlike 3.0 license], which makes the material ineligible for integration into for example Wikimedia projects including Wikipedia. The "NonCommercial" part is contradictory to the business nature of the site. Content in Radlines, on the other hand, is by default licensed as [https://creativecommons.org/licenses/by/4.0/ Attribution 4.0 International license], which will allow the content to be used by more a greater amount of scholarly websites around the world.
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