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*'''====How much contrast can be given?''' ====Evidence suggests that contrast doses should be limited to a ratio of grams of iodine to glomerular filtration rate (I<sub>gram</sub> / GFR<sub>ml/min</sub>) of a maximum of 1.<ref name="KeaneyHannon2013">{{cite journal|last1=Keaney|first1=J. J.|last2=Hannon|first2=C. M.|last3=Murray|first3=P. T.|title=Contrast-induced acute kidney injury: how much contrast is safe?|journal=Nephrology Dialysis Transplantation|volume=28|issue=6|year=2013|pages=1376–1383|issn=0931-0509|doi=10.1093/ndt/gfs602}}</ref> The local practice at NU Hospital Group has a I<sub>gram</sub>/GFR ratio of maximum 0.7 in patients with GFR ≥45 ml/min. It recommends a ratio of maximum 0.5 if GFR is lower, or in the presence of risk factors.
*'''====How much contrast is needed?'''====
→Adjustment of dose: headered
===Adjustment of dose===
Steps to take for potentially performing the CT scan with an adjusted radiocontrast dose are:
{|class="wikitable" align="center"
|+ Volume for various I<sub>gram</sub> / GFR<sub>ml/min</sub> ratios
|}
This depends on the issue at hand. Examples are:
*Liver: Each 1 mg of iodine per kilogram of patient body weight generates a liver enhancement of about 96 HU.<ref name="Bae2010">{{cite journal|last1=Bae|first1=Kyongtae T.|title=Intravenous Contrast Medium Administration and Scan Timing at CT: Considerations and Approaches|journal=Radiology|volume=256|issue=1|year=2010|pages=32–61|issn=0033-8419|doi=10.1148/radiol.10090908}}</ref>
