For the rest of the investigations, evidence suggests that contrast doses should be limited to a ratio of grams of iodine to glomerular filtration rate (I<sub>gram</sub> / GFR<sub>ml/min</sub>) of a maximum of 1.<ref name="KeaneyHannon2013">{{cite journal|last1=Keaney|first1=J. J.|last2=Hannon|first2=C. M.|last3=Murray|first3=P. T.|title=Contrast-induced acute kidney injury: how much contrast is safe?|journal=Nephrology Dialysis Transplantation|volume=28|issue=6|year=2013|pages=1376–1383|issn=0931-0509|doi=10.1093/ndt/gfs602}}</ref> A Swedish practice is to have a I<sub>gram</sub>/GFR ratio of maximum 0.7 in patients with GFR ≥45 ml/min.<ref name=NU>{{NU Hospital Group}}</ref> It recommends a ratio of maximum 0.5 if GFR is lower, or in the presence of risk factors.<ref name=NU/>
{|class="wikitable" align="center"
|+ Volume for various Iodine concentrations! I<sub>gram</sub> / GFR<sub>ml/min</sub> ratios! Iodine<br>concentration ratio !! 1 240 mg/ml !! 0.7 350 mg/ml !! 0.5370 mg/ml
|-
| 240 mg/ml 0.5 || 42.2 1 ml *GFR<sub>ml/min</sub> || 21.9 4 ml *GFR<sub>ml/min</sub> || 21.1 4 ml *GFR<sub>ml/min</sub>
|-
| 350 mg/ml 0.7 || 2.9 ml *GFR<sub>ml/min</sub> || 2.0 ml *GFR<sub>ml/min</sub> || 1.4 9 ml *GFR<sub>ml/min</sub>
|-
| 370 mg/ml 1 || 4.2.7 ml *GFR<sub>ml/min</sub> || 12.9 ml *GFR<sub>ml/min</sub> || 12.4 7 ml *GFR<sub>ml/min</sub>
|}