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→How much contrast is needed: More concentrations
====How much contrast is needed====
{|class="wikitable"
|+ Preferable Sufficient volume for normal weight adults!colspan=2 rowspan=2| Exam !!colspan=23| Iodine concentration !!rowspan=2| Comments
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! 300 mg/ml !! 350 mg/ml !! 370 mg/ml
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|colspan=2| Brain [[CT of the head|CT of brain]] | 80 ml| 95ml<ref name=NZ>{{cite web|url=http://www.medsafe.govt.nz/profs/Datasheet/o/Omnipaqueinj.pdf|title=New Zealand Datasheet|website=New Zealand Medicines and Medical Devices Safety Authority|accessdate=2018-10-16}}</ref> || 80 ml<ref name=NZ/> || 75 ml<ref name=NZ/> ||
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|rowspan=2| Thorax [[CT of the thorax|CT of thorax]] || Overall || 60 70 - 80 95 ml<ref name="IezziLarici2017" group="notes">0.3–0.4 gI/kg in a 70kg individual, according to:*{{cite journal|last1=Iezzi|first1=Roberto|last2=Larici|first2=Anna Rita|last3=Franchi|first3=Paola|last4=Marano|first4=Riccardo|last5=Magarelli|first5=Nicola|last6=Posa|first6=Alessandro|last7=Merlino|first7=Biagio|last8=Manfredi|first8=Riccardo|last9=Colosimo|first9=Cesare|title=Tailoring protocols for chest CT applications: when and how?|journal=Diagnostic and Interventional Radiology|volume=23|issue=6|year=2017|pages=420–427|issn=13053825|doi=10.5152/dir.2017.16615}}</ref> || 60 - 80 ml<ref name="IezziLarici2017" group="notes"/> || 55 - 75 ml<ref name="IezziLarici2017" group="notes"/> || Parenchymal changes of the lung can often be evaluated adequately without the use of intravenous contrast.
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| [[CT of pulmonary embolismangiogram]] || 17 20 ml<ref name="LeroyerMeier2016" group="notes">Using dual energy CTA (such as 90/150SnkVp), according to:*{{cite journal|last1=Leroyer|first1=Christophe|last2=Meier|first2=Andreas|last3=Higashigaito|first3=Kai|last4=Martini|first4=Katharina|last5=Wurnig|first5=Moritz|last6=Seifert|first6=Burkhardt|last7=Keller|first7=Dagmar|last8=Frauenfelder|first8=Thomas|last9=Alkadhi|first9=Hatem|title=Dual Energy CT Pulmonary Angiography with 6g Iodine—A Propensity Score-Matched Study|journal=PLOS ONE|volume=11|issue=12|year=2016|pages=e0167214|issn=1932-6203|doi=10.1371/journal.pone.0167214}}</ref> || 17 ml<ref name="LeroyerMeier2016" group="notes"/> || 15 ml<ref name="LeroyerMeier2016" group="notes"/> || Minimal amount when using specific low-contrast protocol.<ref name="LeroyerMeier2016" group="notes"/>
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|rowspan=2| Abdomen [[CT of the abdomen and pelvis|CT of abdomen]] || Overall || 70 ml<ref name=NZ/> || 60 ml<ref name=NZ/> || 55 ml 60 ml<ref name=NZ/> ||
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| Liver || 45 55 ml<ref name=Liver group="notes">The liver generally needs an enhancement of at least 30 HU for proper evaluation according to:
*{{cite book|title=Multislice CT|edition=3|year=2010|publisher=Springer-Verlag Berlin and Heidelberg GmbH & Co. KG|isbn=9783642069680}}
In males at 30 years of age, there is an estimated 0.027 HU of liver parenchymal enhancement per kilogram of body weight and per gram of iodine, when injected at 4 ml per second, according to:
*{{cite journal|last1=Bae|first1=Kyongtae T.|title=Intravenous Contrast Medium Administration and Scan Timing at CT: Considerations and Approaches|journal=Radiology|volume=256|issue=1|year=2010|pages=32–61|issn=0033-8419|doi=10.1148/radiol.10090908}}
This example takes the example of a man with a typical weight of 70 kg.</ref> || 45 ml<ref name=Liver group="notes"/> || 40-45 ml<ref name=Liver group="notes"/> || Minimal required amount.<ref name=Liver group="notes"/>
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|colspan=2| Angiography [[CT angiography]] ||colspan=2| 20 25 ml<ref name=Angiography group="notes">CT-angiography in a 70kg person, with 100-150 mg I/kg by using 80 kVp, mAs-compensation for constant CNR, fixed injection duration adapted to scan time, automatic bolus tracking and a saline chaser, according to:*{{cite journal|last1=Nyman|first1=Ulf|title=Contrast Medium-Induced Nephropathy (CIN) Gram-Iodine/GFR Ratio to Predict CIN and Strategies to Reduce Contrast Medium Doses|year=2012|doi=10.5772/29992}}</ref> ||colspan=2| 20 ml<ref name=Angiography group="notes"/> || When using specific low-contrast protocol.<ref name=Angiography group="notes"/>
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