As a fictional example, an obese 50 year old male has undergone gastric bypass surgery two days before and has now developed abdominal pain and diarrhea. This is an indication for CT with IV (and oral) contrast.<ref name="LevineCarucci2014">{{cite journal|last1=Levine|first1=Marc S.|last2=Carucci|first2=Laura R.|title=Imaging of Bariatric Surgery: Normal Anatomy and Postoperative Complications|journal=Radiology|volume=270|issue=2|year=2014|pages=327–341|issn=0033-8419|doi=10.1148/radiol.13122520}}</ref> GFR is estimated to be 30 ml/min.
Medical records are checked for additional risk factors, finding diabetes, probable dehydration and anemia. The patient took metformin, but not since the day before surgery. Based on this, it is deemed appropriate to keep a ratio of maximum 1 g iodine/(ml/min of GFR). With the and a local iodine concentration of 350 mg/ml, the amount that can be given is:
*2.9 ml * 30 = 87 ml
*60ml x ((0.00723 × 120) + (0.00474 × 176) − 0.341) = 82 ml
The contrast that can be given is thus slightly less more than is needed. The , yet the patient had additional risk factors, and was probably dehydrated from the diarrhea, and may should therefore be rehydrated before the examif time allows. In an emergency, the patient may need surgery without a prior CT.
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