Difference between revisions of "Contrast medium reaction"

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{{Nutshell|In a more severe reaction:
 
{{Nutshell|In a more severe reaction:
*'''Adrenaline''', 0.3-0.5mg in adults, given intramuscularly, is the most important initial therapy.<ref name=SURF>{{cite web|url=http://www.mastcellssjukdom.se/wp-content/uploads/2015/12/Nationella_rekommendationer_%C3%B6verk%C3%A4nslighetsreaktioner_kontrastmedel__PDF_2014-10-17.pdf|title=Hypersensitivity reactions against contrast media - Swedish Society of Uroradiology [Swedish: Överkänslighetsreaktioner mot kontrastmedel – SURFs kontrastmedelsgrupp] ], 2014-10-17}}</ref>
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*'''Adrenaline''', 0.3-0.5mg in adults, given intramuscularly.<ref name=SURF>{{cite web|url=http://www.mastcellssjukdom.se/wp-content/uploads/2015/12/Nationella_rekommendationer_%C3%B6verk%C3%A4nslighetsreaktioner_kontrastmedel__PDF_2014-10-17.pdf|title=Hypersensitivity reactions against contrast media - Swedish Society of Uroradiology [Swedish: Överkänslighetsreaktioner mot kontrastmedel – SURFs kontrastmedelsgrupp] ], 2014-10-17}}</ref>
*'''Peripheral venous catheter''' and IV fluids are needed<ref name=SURF/>
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*Summon an '''anesthesiologist'''
*'''Oxygen saturation''', '''pulse''' and '''blood pressure''' are monitored.<ref name=SURF/>
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*Insert a '''peripheral venous catheter''' and give IV fluids.<ref name=SURF/>
 
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In case of a '''contrast medium reaction''', a patient should be evaluated for the presence of the following symptoms and be medicated accordingly. Anaphylaxis is a more severe allergic reaction whose diagnostic criteria generally include low blood pressure and/or respiratory distress,<ref name="KimFischer2011">{{cite journal|last1=Kim|first1=Harold|last2=Fischer|first2=David|title=Anaphylaxis|journal=Allergy, Asthma & Clinical Immunology|volume=7|issue=Suppl 1|year=2011|pages=S6|issn=1710-1492|doi=10.1186/1710-1492-7-S1-S6}}</ref> and indicate the attention of an anesthesiologist or corresponding clinician on duty.
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In case of a '''contrast medium reaction''', anaphylaxis is a more severe allergic reaction whose diagnostic criteria generally include low blood pressure and/or respiratory distress.<ref name="KimFischer2011">{{cite journal|last1=Kim|first1=Harold|last2=Fischer|first2=David|title=Anaphylaxis|journal=Allergy, Asthma & Clinical Immunology|volume=7|issue=Suppl 1|year=2011|pages=S6|issn=1710-1492|doi=10.1186/1710-1492-7-S1-S6}}</ref> In anaphylaxis, intramuscularly administered adrenaline is the most important initial therapy.<ref name=SURF/> Also, an '''anesthesiologist''' or corresponding clinician on duty should be summoned. '''Oxygen saturation''', '''pulse''' and '''blood pressure''' are monitored.<ref name=SURF/>
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In general in a contrast medium reaction, the patient should be evaluated for the presence of the following symptoms and be medicated accordingly.<ref name=SURF/>
  
 
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Revision as of 21:12, 22 May 2018

Author: [notes 1]

This page in a nutshell:
In a more severe reaction:
  • Adrenaline, 0.3-0.5mg in adults, given intramuscularly.[1]
  • Summon an anesthesiologist
  • Insert a peripheral venous catheter and give IV fluids.[1]


In case of a contrast medium reaction, anaphylaxis is a more severe allergic reaction whose diagnostic criteria generally include low blood pressure and/or respiratory distress.[2] In anaphylaxis, intramuscularly administered adrenaline is the most important initial therapy.[1] Also, an anesthesiologist or corresponding clinician on duty should be summoned. Oxygen saturation, pulse and blood pressure are monitored.[1]

In general in a contrast medium reaction, the patient should be evaluated for the presence of the following symptoms and be medicated accordingly.[1]

Symptoms[1] Medication[1] Route[1] Dosage[1] Time to effect[1] Repeat[1]
Adults Children
  • Severe hives
  • Respiratory distress
  • Hypotension
  • Altered level of consciousness
  • Severe abdominal pains and vomiting
Injection of adrenaline Intramuscular in lateral thigh 0.3 - 0.5 mg
  • 0.01 mg/kg, up to 0.5 mg
    • 10-20kg: 0.15 mg
    • ≥20kg: 0.3 mg
Less than 5 min Every 5-10 min if needed
Asthma Salbutamol (Ventolin) or own bronchodilator Inhalation
  • 5 mg
  • Usually 4-6 doses
  • 2-6 doses
Less than 5 min Every 10 mins if needed
Hypoxia Oxygen Mask >5 l/min Almost immediate Continuous
Altered level of consciousness or hypotension Volume expander such as Ringer's IV with pressure 20mg/kg Fast As needed
All anaphylaxis cases Antihistamine such as desloratadine (Clarinex/Aerius) Oral 10mg of desloratadine
  • <6 years: 2.5mg desloratadine
  • 6 - 12 years: 5 mg desloratadine
Within 30-60 minutes Usually not
All anaphylaxis cases Glucocorticoid such as betamethasone Oral or IV
  • 5-8 mg betamethasone
  • <6 years: 3-4 mg
  • ≥6 years: 5-8 mg
2-3 hours Usually not

References


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