First-ever seizure

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Author: Mikael Häggström [notes 1]

Choice of modality

In a first-ever unprovoked seizure in adults, MRI of the head is generally the first investigation of choice because of its high sensitivity.[1] However, if MRI is not readily available,[1] or there is continued neurological deficit or other indication of an acute intracranial disease, then initial imaging with head CT is reasonable. If such CT is normal, MRI should still be considered if seizures recur or in the presence of focal electroencephalography (EEG) abnormalities.[1]


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Radlines:Authorship for details.


  1. 1.0 1.1 1.2 Ho, K.; Lawn, N.; Bynevelt, M.; Lee, J.; Dunne, J. (2013). "Neuroimaging of first-ever seizure: Contribution of MRI if CT is normal ". Neurology: Clinical Practice 3 (5): 398–403. doi:10.1212/CPJ.0b013e3182a78f25. ISSN 2163-0402.  American Academy of Neurology