CT in dementia

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Author: Mikael Häggström [notes 1]


Evaluation encompasses the absence of presence of the following:[1]

  • Masses
  • Hydrocephalus: Widening of the ventricles. In suspected hydrocephalus, see CT of hydrocephalus
  • Vascular disease: Territorial infarcts, lacunar strokes, as well as lesions in thalamus or white matter
  • Atrophy, at least for the frontal and temporal lobe
Atrophy (seen as decreased size of gyri and secondary increased size of sulci) by different grading systems:[2]
- Medial temporal lobe atrophy (MTA)
- Posterior atrophy (PA)
- Frontal cortical atrophy (fGCA)


If normal, the report should negate masses, hydrocephalus or signs of vascular disease.

The regions of any atrophy should be specified, but generally do not need to be specified more than mild, moderate or severe, since the important measurements of dementia are clinical and functional.

See also: General notes on reporting


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Radlines:Authorship for details.


  1. Unless else noted in the list, reference is: Andy Adam, Adrian K. Dixon, Jonathan H Gillard, Cornelia Schaefer-Prokop, Ronald G. Grainger, David J. Allison (2014). Grainger & Allison's Diagnostic Radiology (6, revised ed.). Elsevier Health Sciences. ISBN 9780702061288. 
  2. Velickaite, V.; Giedraitis, V.; Ström, K.; Alafuzoff, I.; Zetterberg, H.; Lannfelt, L.; Kilander, L.; Larsson, E-M.; et al. (2017). "Cognitive function in very old men does not correlate to biomarkers of Alzheimer’s disease ". BMC Geriatrics 17 (1). doi:10.1186/s12877-017-0601-6. ISSN 1471-2318.  Creative Commons Attribution 4.0 International License