Changes

Evidence In some emergent conditions such as [[CT of aortic aneurysm]] with suspected rupture, the need for contrast is greater than the risk of contrast-induced nephropathy. For the rest of the investigations, evidence suggests that contrast doses should be limited to a ratio of grams of iodine to glomerular filtration rate (I_gram / GFR_ml/min) of a maximum of 1.<ref name="KeaneyHannon2013">{{cite journal|last1=Keaney|first1=J. J.|last2=Hannon|first2=C. M.|last3=Murray|first3=P. T.|title=Contrast-induced acute kidney injury: how much contrast is safe?|journal=Nephrology Dialysis Transplantation|volume=28|issue=6|year=2013|pages=1376–1383|issn=0931-0509|doi=10.1093/ndt/gfs602}}</ref> The local practice at NU Hospital Group has a I_gram/GFR ratio of maximum 0.7 in patients with GFR ≥45 ml/min. It recommends a ratio of maximum 0.5 if GFR is lower, or in the presence of risk factors.