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CT with IV contrast in low renal function

3 bytes added, 22:17, 9 November 2018
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===Weight adjustment===
The needed dose is proportional to the ''lean body weight'' of the patient. For contrast CT in obese individuals, this is optimally calculated by the Boer formula, using height and weight of the patient.<ref name="CarusoDe Santis2018">{{cite journal|last1=Caruso|first1=Damiano|last2=De Santis|first2=Domenico|last3=Rivosecchi|first3=Flaminia|last4=Zerunian|first4=Marta|last5=Panvini|first5=Nicola|last6=Montesano|first6=Marta|last7=Biondi|first7=Tommaso|last8=Bellini|first8=Davide|last9=Rengo|first9=Marco|last10=Laghi|first10=Andrea|title=Lean Body Weight-Tailored Iodinated Contrast Injection in Obese Patient: Boer versus James Formula|journal=BioMed Research International|volume=2018|year=2018|pages=1–6|issn=2314-6133|doi=10.1155/2018/8521893}}</ref> Taking this formula, the needed volume of IV contrast from the unadjusted volume given in the table above becomes:
*For men: Weight-adjusted volume = Unadjusted volume x × ((0.00723 × W) + (0.00474 × H) − 0.341)*For women: Weight-adjusted volume = Unadjusted volume x × ((0.00583 × W) + (0.011 × H) − 1.12)
, where W is body weight in kilograms and H is body height in centimeters.
With the local iodine concentration being 350 mg/ml, the weight-unadjusted volume needed for the abdominal CT is 60 ml. The patient weights 120 kg and is 176 cm tall. The weight adjusted volume is thus:
*60ml x × ((0.00723 × 120) + (0.00474 × 176) − 0.341) = 82 ml
The contrast that can be given is thus slightly more than is needed, yet the patient had additional risk factors, and was probably dehydrated from the diarrhea, and should therefore be rehydrated before the exam if time allows. In an emergency, the patient may need surgery without a prior CT.
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