|+ CT findings that generally contraindicate thrombolysis<ref name="FrankGrotta2013">{{cite journal|last1=Frank|first1=Benedikt|last2=Grotta|first2=James C.|last3=Alexandrov|first3=Andrei V.|last4=Bluhmki|first4=Erich|last5=Lyden|first5=Patrick|last6=Meretoja|first6=Atte|last7=Mishra|first7=Nishant K.|last8=Shuaib|first8=Ashfaq|last9=Wahlgren|first9=Nils G.|last10=Weimar|first10=Christian|last11=Lees|first11=Kennedy R.|title=Thrombolysis in Stroke Despite Contraindications or Warnings?|journal=Stroke|volume=44|issue=3|year=2013|pages=727–733|issn=0039-2499|doi=10.1161/STROKEAHA.112.674622}}</ref>
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| Edema, dense middle cerebral artery sign, loss of insular ribbon, lenticular hypodensity, acute infarction, sulcal effacement, or ASPECT-score of 8 or 9§9
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| Mass effect, infarction of >1/3 of the middle cerebral artery territory, midline shift, or ASPECT-score of ≤7§≤7
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| ASPECT-score of ≤7