Fibrin sheaths of ports can be suspected when it is possible to infuse into it but not to aspirate.
==Choice of investigationmodality==
Fibrin sheaths are usually detected by fluoroscopic catheter contrast angiography.<ref name="KnutstadHager2016">{{cite journal|last1=Knutstad|first1=K.|last2=Hager|first2=B.|last3=Hauser|first3=M.|title=Radiologic diagnosis and management of complications related to central venous access|journal=Acta Radiologica|volume=44|issue=5|year=2016|pages=508–516|issn=0284-1851|doi=10.1080/j.1600-0455.2003.00115.x}}</ref>