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CT with IV contrast in low renal function

348 bytes added, 20:07, 12 November 2018
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*{{cite journal|last1=Nyman|first1=Ulf|title=Contrast Medium-Induced Nephropathy (CIN) Gram-Iodine/GFR Ratio to Predict CIN and Strategies to Reduce Contrast Medium Doses|year=2012|doi=10.5772/29992}}</ref> ||colspan=2| 20 ml<ref name=Angiography group="notes"/> || When using specific low-contrast protocol.<ref name=Angiography group="notes"/>
|}
 
===Weight adjustment===
The needed dose is proportional to the ''lean body weight'' of the patient. For contrast CT in obese individuals, this is optimally calculated by the Boer formula, using height and weight of the patient.<ref name="CarusoDe Santis2018">{{cite journal|last1=Caruso|first1=Damiano|last2=De Santis|first2=Domenico|last3=Rivosecchi|first3=Flaminia|last4=Zerunian|first4=Marta|last5=Panvini|first5=Nicola|last6=Montesano|first6=Marta|last7=Biondi|first7=Tommaso|last8=Bellini|first8=Davide|last9=Rengo|first9=Marco|last10=Laghi|first10=Andrea|title=Lean Body Weight-Tailored Iodinated Contrast Injection in Obese Patient: Boer versus James Formula|journal=BioMed Research International|volume=2018|year=2018|pages=1–6|issn=2314-6133|doi=10.1155/2018/8521893}}</ref> Taking this formula, the needed volume of IV contrast from the unadjusted volume given in the table above becomes:
*For men: Weight-adjusted volume = Unadjusted volume × ((0.00723 × W) + (0.00474 × H) − 0.341)
*For women: Weight-adjusted volume = Unadjusted volume × ((0.00583 × W) + (0.011 × H) − 1.12)
, where W is body weight in kilograms and H is body height in centimeters.
==Actions==
'''Hydration''' by drinking or intravenous volume expander, either before or after contract administration, decreases the risk of contrast-induced nephropathy.<ref name="YangHiremath2013">{{cite journal|last1=Yang|first1=Xiaoming|last2=Hiremath|first2=Swapnil|last3=Akbari|first3=Ayub|last4=Shabana|first4=Wael|last5=Fergusson|first5=Dean A.|last6=Knoll|first6=Greg A.|title=Prevention of Contrast-Induced Acute Kidney Injury: Is Simple Oral Hydration Similar To Intravenous? A Systematic Review of the Evidence|journal=PLoS ONE|volume=8|issue=3|year=2013|pages=e60009|issn=1932-6203|doi=10.1371/journal.pone.0060009}}</ref>
 
===Underweight or overweight?===
At moderate weight deviations, corrections can be made by adjusting contrast dose proportionally to patient weight. Still, the needed dose is actually proportional to the ''lean body weight'' of the patient. For men weighing over 85 kg and women weighing over 70 kg,<ref group="notes">At above this weight weight, calculated contrast amount with the Boer formula deviates more than 10% from the amount taken proportionally to the weight.</ref> contrast dose is optimally calculated by the Boer formula, using height and weight of the patient.<ref name="CarusoDe Santis2018">{{cite journal|last1=Caruso|first1=Damiano|last2=De Santis|first2=Domenico|last3=Rivosecchi|first3=Flaminia|last4=Zerunian|first4=Marta|last5=Panvini|first5=Nicola|last6=Montesano|first6=Marta|last7=Biondi|first7=Tommaso|last8=Bellini|first8=Davide|last9=Rengo|first9=Marco|last10=Laghi|first10=Andrea|title=Lean Body Weight-Tailored Iodinated Contrast Injection in Obese Patient: Boer versus James Formula|journal=BioMed Research International|volume=2018|year=2018|pages=1–6|issn=2314-6133|doi=10.1155/2018/8521893}}</ref> Taking this formula, the needed volume of IV contrast from the unadjusted volume given in the table above becomes:
*For men: Weight-adjusted volume = Unadjusted volume × ((0.00723 × W) + (0.00474 × H) − 0.341)
*For women: Weight-adjusted volume = Unadjusted volume × ((0.00583 × W) + (0.011 × H) − 1.12)
, where W is body weight in kilograms and H is body height in centimeters.
==Example==
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